Category I: Supporting evidence from in vivo human experiments
Number of EDCs: 9
Chemical nameChemical identifierLiterature identifier
ParaquatDED000241PMID:608823, PMID:8705295
PerchlorateDED000424PMID:12204829, PMID:18560531, PMID:20479570, PMID:29139221
CrizotinibDED000530PMID:23934135
DetirelixDED000541PMID:2005220
AcetaminophenDED000573PMID:23590819, PMID:23670170, PMID:24298046, PMID:26259604, PMID:29665328, PMID:31305161, PMID:32221642, PMID:33098425, PMID:35147701, PMID:35259261, PMID:38657942
IbuprofenDED000587PMID:28281692, PMID:29311296, PMID:29665328
1,2-Dibromo-3-chloropropaneDED000603PMID:25863443, PMID:30219569, PMID:556420, PMID:7663078, PMID:9804871
DiethylstilbestrolDED000665PMID:10210696, PMID:10377036, PMID:10397250, PMID:10641015, PMID:10908838, PMID:11229807, PMID:11961216, PMID:12446607, PMID:12520077, PMID:12589653, PMID:12858341, PMID:14636701, PMID:14695980, PMID:14711791, PMID:14746342, PMID:15016594, PMID:15019959, PMID:15162385, PMID:15166399, PMID:15219628, PMID:15315699, PMID:1537323, PMID:15470002, PMID:15596228, PMID:15597897, PMID:15751030, PMID:16439099, PMID:16723702, PMID:16759992, PMID:16819149, PMID:17010207, PMID:17011747, PMID:17184923, PMID:17213693, PMID:17229994, PMID:17394237, PMID:17558187, PMID:17679765, PMID:18296022, PMID:18692564, PMID:18769493, PMID:19299448, PMID:19734697, PMID:19887736, PMID:20046027, PMID:20172022, PMID:20433902, PMID:20815788, PMID:20932895, PMID:21130156, PMID:21761357, PMID:22569274, PMID:22679223, PMID:22710028, PMID:23314658, PMID:23454116, PMID:23873838, PMID:24002655, PMID:24316331, PMID:24449359, PMID:24533973, PMID:24578295, PMID:24646703, PMID:25062584, PMID:25242112, PMID:25243144, PMID:25852458, PMID:26349937, PMID:26457333, PMID:26970683, PMID:27103539, PMID:27613106, PMID:28031325, PMID:28078498, PMID:28265775, PMID:28734970, PMID:28970132, PMID:29102757, PMID:29752986, PMID:29931162, PMID:30153466, PMID:31084616, PMID:31283846, PMID:31780364, PMID:32370801, PMID:32545544, PMID:32592162, PMID:33012732, PMID:33571642, PMID:33920546, PMID:34207679, PMID:34831106, PMID:35605701, PMID:35834052, PMID:36096261, PMID:36328762, PMID:36488194, PMID:36621641, PMID:36653537, PMID:37077353, PMID:37268149, PMID:37471692, PMID:37511399, PMID:37561284, PMID:37650943, PMID:37689587, PMID:37779174, PMID:37854179, PMID:37856394, PMID:39326550, PMID:39730480, PMID:846001, PMID:9472934
DisulfiramDED000690PMID:13211643, PMID:13258259, PMID:2318350, PMID:347565
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.